Entity Address, City or Town Entity Address, City or Town Deferred tax liabilities: Deferred Tax Liabilities, Net [Abstract] Reconciliation Between Provision for Income Taxes and Income Taxes Computed Using U.S. Federal Statutory Corporate Tax Rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Entity Ex Transition Period Entity Ex Transition Period Paid-in-Kind Interest Issuance of PIK interest debt Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Repurchase right lapse rate Repurchase Right Lapse Rate Repurchase right lapse rate. Change in control description Change in Control Description Change in control description. Domestic Federal Domestic Tax Authority [Member] Issuance of common stock under ATM facility Stock Issued During Period, Value, New Issues Research and Development Expenses and Accruals Research and Development Expense, Policy [Policy Text Block] Long term debt maturities repayments of principal and interest remainder of fiscal year. Long Term Debt Maturities Repayments Of Principal And Interest Remainder Of Fiscal Year 2021 Cash flows from financing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Cashless exercise of common stock warrants, shares Cashless Exercise Of Common Stock Warrants Cashless exercise of common stock warrants. Amendment Flag Amendment Flag Minimum percentage of qualified cash on principal amount prior to third performance milestone. Minimum Percentage of Qualified Cash on Principal Amount Prior to Third Performance Milestone Percentage of qualified cash prior to Third performance milestone Property and equipment purchases included in accounts payable and accrued expenses Capital Expenditures Incurred but Not yet Paid Common stock, shares authorized for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Subsequent Event Type Subsequent Event Type [Domain] Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Employer discretionary match number of shares settled Defined Contribution Plan Employer Discretionary Match Number Of Shares Settled Defined contribution pan employer discretionary match number of shares settled. 401(k) matching contribution, shares 2019 Equity Incentive Plan Two Thousand Nineteen Equity Incentive Plan [Member] 2019 equity incentive plan. Debt Instrument [Table] Schedule of Long-Term Debt Instruments [Table] Debt instrument, prepayment fee percentage of outstanding principal amount Debt Instrument Prepayment Fee Percentage Of Outstanding Principal Amount Debt instrument prepayment fee percentage of outstanding principal amount. Sales commission payable as a percentage of sale of gross sales price per share. Sales Commission Payable as a percentage of sale of Gross Sales Price per share Sales commission payable as a percentage of sale of gross sales price per share Operating loss carryforwards which are carried over indefinitely Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration Warrants expire term Lander Warrants Expire Term Lander warrants expire term. Less: amount representing interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Accrued clinical trial expenses Accrued Clinical Trial Expenses Current Accrued clinical trial expenses current. Net Loss Per Share Earnings Per Share, Policy [Policy Text Block] Statement [Table] Statement [Table] Operating lease liabilities, non-current Operating lease liabilities Operating Lease, Liability, Noncurrent Unrecognized tax benefits that would affect effective tax rate Unrecognized Tax Benefits that Would Impact Effective Tax Rate Cash payments for operating lease costs Operating Lease, Payments Stock Issued During Period, Shares, Employee Stock Purchase Plans ESPP shares issued, shares Number of operating segment Number of Operating Segments Preferred stock, shares outstanding Preferred stock, outstanding shares Preferred Stock, Shares Outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Common stock initially reserved for issuance Common stock reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Auditor Firm ID Vesting of restricted shares and restricted stock units Stock Issued During Period, Shares, Restricted Stock Award And Restricted Stock Units Stock issued during period, shares, restricted stock award and restricted stock units. Weighted Average Grant Date Fair Value Per Share, Unvested Beginning Balance Weighted Average Grant Date Fair Value Per Share, Unvested Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value Per Share, Vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Income Tax Authority Income Tax Authority [Domain] Share vesting Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Share Vesting Share-based compensation arrangement by share-based payment award, equity instruments other than options, share vesting. Purchase of additional offering expenses Purchase Of Additional Offering Expenses Purchase of additional offering expenses. Lease Commitments Lessee, Operating Leases [Text Block] Stock Options Share-Based Payment Arrangement, Option [Member] Weighted-average remaining lease term (in years) Operating Lease, Weighted Average Remaining Lease Term Share based compensation arrangement by share based payment award, options and other than options, grants in period gross. Share Based Compensation Arrangement By Share Based Payment Award Options and Other than Options, Grants In Period Gross Number of shares, granted Total liabilities and stockholders’ equity Liabilities and Equity Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards [Line Items] Revenue Interest Financing Liability Revenue Interest Financing Liability [Text Block] Revenue interest financing liability. Plan Name Plan Name [Domain] Fair value adjustment of warrants Fair Value Adjustment of Warrants Change in fair value of warrant liabilities Change in fair value of warrant liabilities Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Income Statement [Abstract] Other Effective Income Tax Rate Reconciliation, Other Adjustments, Amount Nonfinancial assets fair value disclosure. Nonfinancial Assets Fair Value Disclosure Non-financial assets fair value disclosure Non-financial liabilities fair value disclosure Nonfinancial Liabilities Fair Value Disclosure Nonfinancial Liabilities Fair Value Disclosure, Total Sale of Stock Sale of Stock [Domain] Proceeds from the Revenue Interest Financing Agreement Gross proceeds Gross Proceeds from Revenue Interest Financing Agreement Gross proceeds from revenue interest financing agreement. Total current liabilities Liabilities, Current Stock Issued During Period, Value, Employee Stock Purchase Plan ESPP shares issued Operating Loss Carryforwards, Total Operating Loss Carryforwards Net operating loss carryforwards 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Common stock warrants Common Stock Warrant [Member] Common stock warrants. Fair Value, Recurring Fair Value, Recurring [Member] Interest Expense Interest Expense, Total Interest expense Income Taxes Income Tax, Policy [Policy Text Block] Agreement expiration term from date of first commercial sale Agreement Expiration Term From Date Of First Commercial Sale Agreement expiration term from date of first commercial sale. Maximum percentage of eligible compensation contributed by participants Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate Preferred stock, shares authorized Preferred stock, authorized shares Preferred Stock, Shares Authorized Net proceeds from issuance of common stock Net Proceeds From Issuance Of Common Stock Net proceeds from issuance of common stock. Treasury stock shares ending balance Treasury stock shares ending balance Treasury Stock, Shares Treasury Stock, Shares, Total Additional warrant issued Additional Warrant Issued Additional warrant issued. Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Stock options and performance-based units. Stock options and performance-based units [Member] Stock Options and Performance-based Units Weighted-average incremental borrowing rate Operating Lease, Weighted Average Discount Rate, Percent Revenue Interest Financing Agreement Revenue Interest Financing Agreement [Member] Revenue Interest Financing Agreement [Member] Organization Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items] Organization Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items] Organization basis of presentation and summary of significant accounting policies. Variable Rate Variable Rate [Axis] Entity Small Business Entity Small Business Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Stock-Based Compensation Compensation Related Costs, Policy [Policy Text Block] Revenue Interest Financing Liability Revenue Interest Financing Liability [Policy Text Block] Revenue interest financing liability. Remaining number of shares to be repurchased Stock Repurchase Program, Remaining Number of Shares Authorized to be Repurchased Cash consideration paid for license Payment For License Amount Payment for license amount. Payment in kind PIK interest rate. Payment in Kind PIK Interest Rate [Member] Payment In Kind PIK Interest Rate Total current assets Assets, Current Property Plant And Equipment [Line Items] Property, Plant and Equipment [Line Items] Related parties accounts payable and accrued expenses Increase Decrease In Accounts Payable And Accrued Expenses Related Parties Increase (decrease) in accounts payable and accrued expenses related parties. Weighted-average shares of common stock outstanding, basic Weighted Average Number of Shares Outstanding, Basic Weighted Average Number of Shares Outstanding, Basic, Total Operating lease liabilities arising from obtaining right-of-use assets Operating Lease Liabilities Arising From Obtaining Right Of Use Assets Operating lease liabilities arising from obtaining right-of-use assets Commitments And Contingencies [Table] Commitments And Contingencies [Table] Commitments and contingencies. City Area Code City Area Code Aggregate Intrinsic Value, Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Long-term debt, non-current portion Long Term Debt Noncurrent Excluding Unamortized Debt Discount Long term debt noncurrent excluding unamortized debt discount. Prepaid expenses and other current assets, related parties Prepaid Expenses And Other Assets Related Parties Current Prepaid expenses and other assets related parties current. Options Outstanding, Options cancelled Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Options Outstanding, Options cancelled Options cancelled or forfeited Share-Based Payment Arrangement [Abstract] Total liabilities Liabilities Document Period End Date Document Period End Date Stock issuance costs Payments of Stock Issuance Costs Loan Agreement Loan Agreement [Member] Loan agreement. Restricted Stock Restricted Stock [Member] Annual increase to shares available for issuance percentage of outstanding common stock Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum 2026 Long Term Debt Maturities Repayments Of Principal And Interest In Year Four Long term debt maturities repayments of principal and interest in year four. Construction in Process Construction in Progress [Member] In Process Research and Development, Policy [Policy Text Block] In-Process Research and Development Estimated weighted-average fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Operating lease, renewal term Lessee, Operating Lease, Renewal Term Fair value liability, transfers into level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Liability, Transfers Into Level 3 First Anniversary Share-Based Payment Arrangement, Tranche One [Member] Statistical Measurement Statistical Measurement [Axis] Accounts payable, related parties Accounts Payable, Related Parties, Current Investors right to receive royalties termination description Investors Right to Receive Royalties Termination Description Investors right to receive royalties termination description. Prepaid Lease Payments Prepaid Lease Payments [Member] Prepaid lease payments. Subsequent Event [Line Items] Balance Sheet Details Component Of Balance Sheet Disclosure [Text Block] Component of Balance Sheet Disclosure. Related Party Related Party [Axis] Percentage of investor share of royalty in net sales Percentage of Investor Share of Royalty in Net Sales Percentage of investor share of royalty in net sales. Total assets Assets Research and development expenditures, amortization period Tax Cuts and Jobs Act, Research and Development Expenditures Amortization Period Tax cuts and jobs act, research and development expenditures amortization period. State and Local Jurisdiction [Member] State Long-term debt, net of discount Long-Term Debt, Excluding Current Maturities Long-term Debt, Excluding Current Maturities, Total Net loss per share, diluted Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Stock Repurchase Program Expiration Month and Year Stock repurchase program expiration period Accrued expenses, related parties Accrued Expenses Related Parties Current Accrued expenses related parties current. Entity Address, Postal Zip Code Entity Address, Postal Zip Code Document Fiscal Period Focus Document Fiscal Period Focus Stock repurchase program, period in force Stock Repurchase Program, Period in Force Restricted cash Restricted Cash Restricted Cash, Total Summary of Supplemental Balance Sheet Information Related to the Operating Leases Summary Of Supplemental Balance Sheet Information Related To Operating Leases Table [Text Block] Summary of supplemental balance sheet information related to operating leases. Warrants exercisable shares of common stock Lender Warrants Exercisable Shares Of Common Stock Lender warrants exercisable shares of common stock. 401(k) Plan Defined Contribution Plan [Text Block] Less valuation allowance Deferred Tax Assets, Valuation Allowance Deferred Tax Assets, Valuation Allowance, Total Preferred stock, $0.0001 par value; authorized shares - 40,000,000 at December 31, 2022 and 2021; no shares issued and outstanding at December 31, 2022 and 2021 Preferred Stock, Value, Issued Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Ending Balance Preferred stock, $0.0001 par value authorized shares 40,000,000 at December 31, 2020 and 2019 no shares issued and outstanding at December 31, 2020 and 2019 Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Initial Investors NQ, Sagard, and Hercules Initial Investors NQ, Sagard, and Hercules [Member] Initial Investors NQ, Sagard, and Hercules. Interest income Investment Income, Interest Counterparty Name [Domain] Purchase obligation in the first 24-month period Purchase Obligation Due In First Twenty Four Months Purchase obligation due in first twenty four months. Total operating lease liabilities Operating Lease, Liability Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Noncash issuance of common stock warrants in connection with long term debt. Noncash Issuance Of Common Stock Warrants In Connection With Long Term Debt Issuance of common stock warrants in connection with long-term debt Contract with Customer, Liability [Table] Contract with customer, liability. Impairment losses Impairment of Long-Lived Assets to be Disposed of Statement of Financial Position [Abstract] Securities Act File Number Entity File Number Statement of Cash Flows [Abstract] Contract with Customer, Liability [Abstract] Balance Sheet Related Disclosures [Abstract] Minimum market capitalization amount. Minimum Market Capitalization Amount Minimum market capitalization amount Beginning liability balance Ending liability balance Revenue interest financing liability Revenue Interest Financing Liability Revenue interest financing liability. Warrants issued to purchase shares Class of Warrant or Right, Number of Securities Called by Warrants or Rights Warrants issued to purchase shares Geographical Geographical [Domain] Statistical Measurement Statistical Measurement [Domain] Statement of Stockholders' Equity [Abstract] Sale of Stock Sale of Stock [Axis] Auditor Location Revenue Interest Financing Agreement Upon Occurrence of Event of Default between April 1, 2025, and April 1, 2028 Revenue Interest Financing Agreement Upon Occurrence of Event of Default Between April One Two Thousand and Twenty Five and April One Two Thousand and Twenty Eight [Member] Revenue interest financing agreement upon occurrence of event between April one two thousand and twenty five and April one two thousand and twenty eight. Subsequent Events [Abstract] Weighted-Average Remaining Contractual Term, Options exercisable as of December 31, 2022 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Proceeds from issuance of common stock from exercise of stock options Proceeds from Stock Options Exercised Proceeds from issuance of shares Proceeds from Issuance of Common Stock Net proceeds from issuance of common stock Debt instrument interest rate Debt Instrument, Interest Rate Percentage Debt instrument, interest rate percentage. Long-term Debt, Type Long-Term Debt, Type [Axis] Grantee Status Grantee Status [Axis] Research and development credits Research credits Deferred Tax Assets, Tax Credit Carryforwards, Research ILLINOIS Buffalo Grove, Illinois Schedule of Property, Plant and Equipment, Net Property, Plant and Equipment [Table Text Block] Research and development credits expiration period Research And Development Tax Credit Carry Forward Expiration Year Research and development tax credit carry forward expiration year. Related parties prepaid expenses and other assets current Increase Decrease In Prepaid Expenses And Other Assets Related Parties Current Increase (decrease)in prepaid expenses and other assets related parties current. Concentrations of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Antidilutive Securities Antidilutive Securities [Axis] Expense related to services Related Party Transaction, Expenses from Transactions with Related Party Preferred stock, par value Preferred Stock, Par or Stated Value Per Share Lessee Lease Description [Line Items] Lessee, Lease, Description [Line Items] Closing market price of common stock Closing Market Price Of Common Stock Closing market price of common stock. Subsequent Events Subsequent Events [Text Block] Revenue Interest Financing Liability [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Weighted-average shares of common stock outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted Weighted Average Number of Shares Outstanding, Diluted, Total Organization, Basis of Presentation and Summary of Significant Accounting Policies Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Unrecognized stock-based compensation expense Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Computer Equipment and Software Computer Equipment [Member] General and Administrative Expense General and Administrative Expense [Member] Organization Basis Of Presentation And Summary Of Significant Accounting Policies [Table] Organization Basis Of Presentation And Summary Of Significant Accounting Policies [Table] Organization basis of presentation and summary of significant accounting policies. Unrecognized stock-based compensation expense Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Current Fiscal Year End Date Current Fiscal Year End Date Depreciation expense Depreciation Depreciation, Total Schedule of Total Revenue Interest Financing Liability Schedule of Revenue Interest Financing Liability [Table Text Block] Schedule of revenue interest financing liability. Cash and cash equivalents – beginning of period Cash and cash equivalents – end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Repurchases of shares Stock Repurchased During Period, Shares Other long-term assets Other Assets, Noncurrent Other Assets, Noncurrent, Total Entity Address, Address Line One Entity Address, Address Line One Repayments of Long-term Debt, Total Repayments of Long-Term Debt Repayment of long-term debt Document Annual Report Document Annual Report Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Summary of Weighted-Average Assumptions Used to Estimate Fair Value of ESPP Awards 2023 Long Term Debt Maturities Repayments Of Principal And Interest Due Next Twelve Months Long term debt maturities repayments of principal and interest, year one. Non Cash Settlement Of Defined Contribution Plan Liability In Common Stock Settlement of 401(k) liability in common stock NonCash settlement of defined contribution plan liability in common stock. Accrued Liabilities, Current [Abstract] Supplemental disclosure of cash flow information Supplemental Cash Flow Information [Abstract] Components of Deferred Tax Assets [Abstract] Frazier Principal Owner [Member] ESPP Plan Employee Stock Purchase Plan Employee Stock Purchase Plan [Member] Employee stock purchase plan. Change in fair value of warrants and convertible debt Income Tax Reconciliation Change In Fair Value Of Warrants And Convertible Debt Income tax reconciliation change in fair value of warrants and convertible debt. Provision for income taxes Provision (benefit) for income taxes Income Tax Expense (Benefit) 2025 Long Term Debt Maturities Repayments Of Principal And Interest In Year Three Long term debt maturities repayments of principal and interest in year three. Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Income Taxes Income Tax Disclosure [Text Block] Vesting Vesting [Axis] Preferred stock, shares issued Preferred stock, issued shares Preferred Stock, Shares Issued Preferred Stock, Shares Issued, Total Balance Sheet Location Balance Sheet Location [Domain] Research and development expenses, related party Research And Development Expense Related Party Research and development expense related party. Accrued other Other Accrued Liabilities, Current Cash paid for property, plant and equipment Payments to Acquire Property, Plant, and Equipment Payments to Acquire Property, Plant, and Equipment, Total Income Tax Disclosure [Abstract] Accrued interest Increase (Decrease) in Interest Payable, Net Outstanding accounts payable and accrued expenses Accounts Payable And Accrued Expenses Related Parties Current Accounts payable and accrued expenses related parties current. Issuance of common stock under ATM facility, shares Shares issued Common stock shares issued General and administrative expenses, related party General And Administrative Expense Related Party General and administrative expense related party. Investors receipt description Investors Receipt Description Investors receipt description. Minimum percentage of qualified cash on principal amount following third performance milestone. Minimum Percentage of Qualified Cash on Principal Amount Following Third Performance Milestone Minimum percentage of qualified cash following third performance milestone Drug product Or substance. Drug Product Or Substance [Member] Drug Product or Substance Percentage of debt funded to be issued as warrants to purchase common stock. Percentage of Debt Funded to be Issued as Warrants to Purchase Common Stock Percentage of debt funded to be issued as warrants to purchase common stock Shared operating expenses Related Party Transaction Shared Operating Expenses Due To Transactions With Related Party Related party transaction shared operating expenses due to transactions with related party. Non Cash Settlement Of Employee Stock Purchase Plan Liability In Common Stock Settlement of ESPP liability in common stock NonCash settlement of employee stock purchase plan liability in common stock. Class of warrant or right, number of securities called by warrants or rights, remains exercisable. Class of Warrant or Right, Number of Securities Called by Warrants or Rights, Remains Exercisable Warrants issued to common stock remains exercisable Warrants issued to common stock remains exercisable Auditor Name General and Administrative Expenses Selling, General and Administrative Expenses, Policy [Policy Text Block] Weighted-Average Exercise Price, Options cancelled Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Loss from operations Operating Income (Loss) Number of warrants remaining exercisable Number of Warrants Remaining Exercisable Number of warrants remaining exercisable. Debt Instrument, Interest Rate, Stated Percentage Debt instrument, interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Number of shares issued Operating lease, option to extend description Lessee, Operating Lease, Option to Extend Related Party Related Party [Domain] Additional paid-in capital Additional Paid in Capital, Common Stock Additional Paid in Capital, Common Stock, Beginning Balance Additional Paid in Capital, Common Stock, Ending Balance Debt issuance costs Unamortized Debt Issuance Expense Accrued professional & consulting expenses Accrued Professional Fees, Current Class of Warrant or Right Class of Warrant or Right [Domain] Entity Filer Category Entity Filer Category Summary of Unvested Shares Schedule of Unvested Restricted Stock Units Roll Forward [Table Text Block] Total operating expenses Operating Expenses Entity Current Reporting Status Entity Current Reporting Status Vesting of restricted shares Stock Issued During Period, Value, Restricted Stock Award, Gross Liabilities: Liabilities Lessee [Abstract] Liabilities, lessee. ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Aggregate Intrinsic Value, Options exercisable as of December 31, 2022 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Prime Rate Prime Rate [Member] Liquidity and Capital Resources Liquidity And Capital Resources Policy [Text Block] Liquidity and capital resources. Number of shares remain available for issuance, annual increase Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Annual Increase Share based compensation arrangement by share based payment award number of shares available for grant annual increase. Class of Warrant or Right Expire Term Warrants expire term Class of warrant or right, expire term. Term Loan [Member] Term loan. Term Loans Term Loan Amount utilized of equity financing Amount Utilized of equity financing Amount Utilized of equity financing. 2024 Long Term Debt Maturities Repayments Of Principal And Interest In Year Two Long term debt maturities repayments of principal and interest in year two. Cashless exercise of common stock warrants Stock Issued During Period Shares Cashless Exercise of Common Stock Warrants Stock issued during period shares cashless exercise of common stock warrants. Total stockholders' (deficit) equity Beginning balance Ending balance Stockholders' Equity Attributable to Parent Base Rate [Member] Floor Rate Documents Incorporated by Reference [Text Block] Documents Incorporated by Reference Entity Tax Identification Number Entity Tax Identification Number Income Statement Location Income Statement Location [Axis] Number of Stock Units, Forfeited Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Number of Stock Units, Forfeited Common stock, $0.0001 par value; authorized shares - 400,000,000 at December 31, 2022 and 2021; issued shares - 41,723,308 and 31,656,035 at December 31, 2022 and 2021, respectively; outstanding shares - 41,468,871 and 30,511,226 at December 31, 2022 and 2021, respectively Common stock fair value Common Stock, Value, Issued Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Accumulated deficit Retained Earnings (Accumulated Deficit) Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Ending Balance Available equity financing amount Available Aggregate offering price through equity financing Available Aggregate offering price through equity financing. Equity Components Equity Components [Axis] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Leases [Abstract] Accounts payable and accrued expenses (includes changes in related party amounts of $1,139 and $2,766, respectively) Increase (Decrease) in Accounts Payable and Accrued Liabilities Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total Entity Emerging Growth Company Entity Emerging Growth Company Related Party Transaction Related Party Transaction [Axis] Fair value liability, transfers out of level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Liability, Transfers out of Level 3 Operating expenses: Operating Expenses [Abstract] Revenue Interest Financing Agreement Upon Occurrence of Event of Default Prior to April 1, 2025 Revenue Interest Financing Agreement Upon Occurrence of Event of Default prior to April One Two thousand and Twenty Five [Member] Revenue interest financing agreement upon occurrence of event of default prior to April one two thousand and twenty five. Interest expense Interest Expense, Debt Interest Expense, Debt, Total Agreement extends period for termination Agreement Extends Period For Termination Agreement extends period for termination. Summary of Common Stock Reserved for Future Issuance Common Stock Reserved For Future Issuances Table Table [Text Block] Common stock reserved for future issuances. Issuance of common stock warrants Adjustments to additional paid-in-capital, warrants issued Adjustments to Additional Paid in Capital, Warrant Issued Partner Type Partner Type [Axis] Stock Options and Performance-Based Awards Outstanding Stock Options And Performance Based Awards [Member] Stock options and performance-based awards. Revenue Interest Financing Agreement Upon Occurrence of a Change in Control Event Earlier of April 1, 2024 or FDA Approval If Occurrence Prior May 3, 2023 Revenue Interest Financing Agreement Upon Occurrence of a Change in Control Event Earlier of April One Two Thousand and Twenty Four or FDA Approval If Occurrence Prior to May Three Two Thousand and Twenty Three [Member] Revenue interest financing agreement upon occurrence of a change in control event earlier of April one two thousand and twenty four or FDA approval If occurrence is prior to May three two thousand and twenty three. Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Clinical Manufacturing Services Clinical Manufacturing Services [Member] Clinical manufacturing services. Employee and Nonemployee Director Share Based Payment Arrangement Employee And Nonemployee [Member] Share-based payment arrangement, employee and nonemployee. Entity Voluntary Filers Entity Voluntary Filers Retirement Benefits [Abstract] Document Transition Report Document Transition Report Investors funding amount Investors Funding Amount Investors funding amount. Weighted Average Grant Date Fair Value Per Share, Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Revenue Interest Financing Agreement Upon Occurrence of a Change in Control Event Earlier of April 1, 2024 or FDA approval If occurrence is Thereafter to May 3, 2023 Revenue Interest Financing Agreement Upon Occurrence of a Change in Control Event Earlier of April One Two Thousand and Twenty Four or FDA approval If occurrence is Thereafter to May Three Two Thousand and Twenty Three [Member] Revenue interest financing agreement upon occurrence of a change in control event earlier of April one two thousand and twenty four or FDA approval If occurrence is thereafter to May three two thousand and twenty three. Total other expense Total other income (expense) Nonoperating Income (Expense) Depreciation and amortization Depreciation, Depletion and Amortization Depreciation, Depletion and Amortization, Total Purchase price per share after deducting underwriting discounts and commissions Shares Issued Price Per Share After Deductions Shares issued, price per share after deductions. Common stock, price per share Sale of Stock, Price Per Share Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Plus: interest expense Interest expense with revenue interest finance liability Interest Expense Related To Revenue Interest Financing Liability Interest expense related to revenue interest financing liability Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Issuance of common stock warrants shares Stock issued during period shares exercise of warrants. Issuance of common stock from exercise of warrants, shares Transaction costs License Agreement Transaction Costs License agreement transaction costs. Amortization of debt discount Amortization of Debt Issuance Costs Net loss and comprehensive loss Net loss Net Income (Loss) Attributable to Parent Term loans, aggregate principal amount tranches two. Term Loans Aggregate Principal Amount Tranches Two [Member] Term Loans, Aggregate Principal Amount Tranches Two Assets: Assets Lessee [Abstract] Assets, lessee. Less: operating lease liabilities, current Operating lease liabilities, current Operating Lease, Liability, Current Investors additional funding amount upon FDA approval of vonoprazan for treatment of erosive esophagitis Investor Additional Funding Amount Upon Approval Investor additional funding amount upon approval. Additional Paid-in Capital Additional Paid-in Capital [Member] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Deferred Tax Assets, Operating Loss Carryforwards, Total Schedule of Future Minimum Principal Payments Under Term Loans Schedule of Maturities of Long-Term Debt [Table Text Block] Florham Park, New Jersey JERSEY Follow on public offering. Follow On Public Offering [Member] Follow-on Public Offering Entity Registrant Name Entity Registrant Name Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Ending Balance Number of shares authorized to repurchase Stock Repurchase Program, Number of Shares Authorized to be Repurchased Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Summary of Weighted-Average Assumptions Used to Estimate Fair Value of Stock Options Class of Warrant or Right Expiration Date Warrants expiration date Class of warrant or right, expiration date. Accrued interest Accrued Interest Accrued interest. Debt instrument, maturity date Debt Instrument, Maturity Date Lessee Lease Description [Table] Lessee, Lease, Description [Table] Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Share-based Payment Arrangement, Noncash Expense, Total Total property, plant and equipment, net Property, plant and equipment, net Property, Plant and Equipment, Net Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Weighted-Average Remaining Contractual Term, Options vested and expected to vest Unamortized debt discount Debt Instrument, Unamortized Discount Debt Instrument, Unamortized Discount, Total Award Type Award Type [Domain] Statement [Line Items] Statement [Line Items] Stock options, PSUs and RSUs Stock Option Performance-based Unit and Restricted Stock Unit [Member] Stock option performance-based unit and restricted stock unit. Percentage of aggregate payments on investment amount to investors on net sales Percentage Of Aggregate Payments On Investment Amount To Investors On Net Sales Percentage of aggregate payments on investment amount to investors on net sales. Operating leases, rent expense Operating Lease, Expense Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Weighted-Average Exercise Price, Options vested and expected to vest Title of 12(b) Security Title of 12(b) Security Revenue interest financing liability Revenue Interest Financing Liability Noncurrent Revenue interest financing liability noncurrent. Common Stock Common Stock [Member] Cash flows from operating activities Net Cash Provided by (Used in) Operating Activities [Abstract] Hercules Loan Agreement Hercules Loan Agreement [Member] Hercules loan agreement. Equity Component Equity Component [Domain] Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Computer Equipment and Related Software Computer Equipment And Software [Member] Computer equipment and software. Term loans, aggregate principal amount tranches three. Term Loans Aggregate Principal Amount Tranches Three [Member] Term Loans, Aggregate Principal Amount Tranches Three Entity Address, State or Province Entity Address, State or Province Geographical Geographical [Axis] Debt instrument, final payment fee percentage Debt Instrument Final Payment Fee Percentage Debt instrument final payment fee percentage. 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