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Weighted Average Grant Date Fair Value Per Share, Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Security Exchange Name Security Exchange Name Accounts Receivable, Net Accounts Receivable [Policy Text Block] Domestic Domestic Tax Authority [Member] Weighted-Average Exercise Price, Options exercised Share Based Compensation Arrangements By Share Based Payment Award Options Exercises And Shares Vested In Period Weighted Average Exercise Price Share based compensation arrangements by share based payment award options exercises and shares vested in period weighted average exercise price. 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Weighted-Average Exercise Price, Beginning Balance Weighted-Average Exercise Price, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Revenue ​interest​ financing​ agreement​ funding upon FDA approval at any time prior to December thirty one two thousand and twenty two. Revenue Interest Financing Agreement Funding Upon FDA Approval At Any Time prior To December Thirty One Two Thousand and Twenty Two [Member] Revenue Interest Financing Agreement Funding upon FDA Approval at any Time Prior to December 31, 2022 Accrued research and development expenses Accrued Research And Development Expenses Accrued research and development expenses. At-the-Market Offering Program A T M Offering Program [Member] At-the-market offering program. Disaggregation of Revenue [Line Items] Leasehold Improvements Leasehold Improvements [Member] Income Tax Authority [Axis] Accounts receivable, net Receivables, Net, Current Receivables, Net, Current, Total Annual increase to shares available for issuance percentage of outstanding common stock Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Measurement Frequency Measurement Frequency [Domain] Payments to Acquire Property, Plant, and Equipment, Total Cash paid for property, plant and equipment Payments to Acquire Property, Plant, and Equipment Number of Stock Units, Vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Number of Stock Units, Vested Shares issued Issuance of common stock, shares Common stock shares issued Operating leases, rent expense Operating Lease, Expense Debt instrument, facility charge percentage Debt Instrument Facility Charge Percentage Debt instrument facility charge percentage. Potential additional investor funding amount. Potential Additional Investor Funding Amount Potential additional investor funding amount Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Cash and cash equivalents and restricted cash - beginning of period Cash and cash equivalents and restricted cash - end of period Class of Warrant or Right Class of Warrant or Right [Axis] Organization and Basis of Presentation Organization and Basis of Presentation [Policy Text Block] Organization and basis of presentation.